First, let's define the root word REGENERATE.

1. Regenerate
   1. To generate or produce anew; to reproduce.
   2. In theology, to renew the heart by a change of affections; to change the heart and affections from natural enmity to the love of God; to implant holy affections in the heart.
2. Regenerate
   1. Reproduced.
   2. Born anew; renovated in heart; changed from a natural to a spiritual state.

Now, for the sake of completeness; the prefix UN.

1. Un
   1. A prefix or inseparable preposition, un or on, usually un, an, is the same word as the L. in.
      It is a particle of negation, giving to words to which it is prefixed, a negative signification. We use un or in indifferently for this purpose; and the tendency of modern usage is to prefer the use of in, in some words, where un was formerly used.
      Un admits of no change of n into l, m or r, as in does, in illuminate, immense, irresolute. It is prefixed generally to adjectives and participles, and almost at pleasure.
      In a few instances, it is prefixed to verbs, as in unbend, unbind, unharness. As the compounds formed with un are so common and so well known, the composition is not noticed under the several words. For the etymologies (derivative of), see the simple words.

All this is saying is that the us of "UN" with a word negates it. So, the word unregenerate refers to a person who has not changed. In other words, their heart and lifestyle has not changed from a previous state.

Now, to English 201... just kidding.

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